In Vitro Permeation Test (IVPT)
An In Vitro Permeation Test (IVPT) study is a laboratory method used to evaluate the permeability and rate of drug absorption through the skin from topical formulations. These studies are conducted using skin samples from humans or animals mounted on diffusion cells to simulate the human skin barrier.
IVPT is performed to predict the cutaneous pharmacokinetics of the drug. We perform IVPT studies across various biological membranes such as human cadaver skin, porcine skin, nail, and cornea following various conditions such as finite and infinite dosing, occluded and nonoccluded conditions using Franz diffusion cells.
